In this course, chemistry will mainly be understood as reactions. The course gives an overview about the basics of reaction chemistry and discuss what is already known and what can be measured in the laboratory nowadays (i.e. describing the current frontiers and where the research performed at CFEL can make a difference). In the biochemistry part, the basic principles of nucleic acids (DNA, RNA, their replication etc.) and proteins, their structure and function etc. will be discussed. It will be interesting to work out where the new coherent sources can advance the field.