Publications of E.-C. Schulz

A. Berkes, S. Kleine-Doepke, J.-P. Leimkohl, H. Schikora, P. Mehrabi, F. Tellkamp, and E.-C. Schulz, An electropneumatic cleaning device for piezo-actuator-driven picolitre-droplet dispensers, Journal of Applied Crystallography 57 (1), 209–214 (2024).

P. Mehrabi, S. Sung, D. von Stetten, A. Prester, C. E. Hatton, S. Kleine-Döpke, A. Berkes, G. Gore, J.-P. Leimkohl, H. Schikora, M. Kollewe, H. Rohde, M. Wilmanns, F. Tellkamp, and E.-C. Schulz, Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography, Nature Communications 14 (1), 2365 (2023).

L. Bultema, R. Bücker, E.-C. Schulz, F. Tellkamp, J. Gonschior, R. J. D. Miller, and G. Kassier, The effect of secondary electrons on radiolysis as observed by in liquid TEM: The role of window material and electrical bias, Ultramicroscopy 240, 113579 (2022).

B. Norton-Baker, P. Mehrabi, J. Boger, R. Schönherr, D. von Stetten, H. Schikora, A. O. Kwok, R. W. Martin, R. J. D. Miller, L. Redecke, and E.-C. Schulz, A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip, Acta Crystallographica Section D: Structural Biology 77 (6), D77 (2021).

S. Günther, P. Y. A. Reinke, Y. Fernández-García, J. Lieske, T. J. Lane, H. M. Ginn, F. H. M. Koua, C. Ehrt, W. Ewert, D. Oberthuer, O. Yefanov, S. Meier, K. Lorenzen, B. Krichel, J.-D. Kopicki, L. Gelisio, W. Brehm, I. Dunkel, B. Seychell, H. Gieseler, B. Norton-Baker, B. Escudero-Pérez, M. Domaracky, S. Saouane, A. Tolstikova, T. A. White, A. Hänle, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, M. Barthelmess, F. Schlünzen, L. X. Paulraj, N. Werner, H. Andaleeb, N. Ullah, S. Falke, V. Srinivasan, B. A. Franca, M. Schwinzer, H. Brognaro, C. Rogers, D. Melo, J. J. Zaitsev-Doyle, J. Knoska, G. E. P. Murillo, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, J. Hakanpää, J. Meyer, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, A. R. Beccari, G. Bourenkov, D. von Stetten, G. Pompidor, I. Bento, S. Panneerselvam, I. Karpics, T. R. Schneider, M. M. G. Alai, S. Niebling, C. Günther, C. Schmidt, R. Schubert, H. Han, J. Boger, D. C. F. Monteiro, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. G. Feiler, M. S. Weiss, E.-C. Schulz, P. Mehrabi, K. Karničar, A. Usenik, J. Loboda, H. Tidow, A. Chari, R. Hilgenfeld, C. Uetrecht, R. Cox, A. Zaliani, T. Beck, M. Rarey, S. Günther, D. Turk, W. Hinrichs, H. N. Chapman, A. .R. Pearson, C. Betzel, and A. Meents, X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease, Science 372 (6542), 642–646 (2021).

P. Mehrabi, R. Bücker, G. Bourenkov, H. Ginn, D. von Stetten, H. M. Mueller-Werkmeister, A. Kuo, T. Morizumi, B. Eger, W.-L. Ou, S. Oghbaey, A. Sarracini, J. Besaw, O. Paré-Labrosse, S. Meier, H. Schikora, F. Tellkamp, A. Marx, D. A. Sherrell, D. Axford, R. L. Owen, O. P. Ernst, E. F. Pai, E.-C. Schulz, and R. J. D. Miller, Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison, Science Advances 7 (12), eabf1380 (2021).

S. Azim, L. Bultema, M. de Kock, E. R. Osorio-Blanco, M. Calderón, J. Gonschior, J.-P. Leimkohl, F. Tellkamp, R. Bücker, E.-C. Schulz, S. Keskin, N. de Jonge, G. Kassier, and R. J. D. Miller, Environmental Liquid Cell Technique for Improved Electron Microscopic Imaging of Soft Matter in Solution, Microscopy and Microanalysis 27 (1), 44–53 (2021).

E.-C. Schulz, S. R. Henderson, B. Illarionov, T. Crosskey, S. M. Southall, B. Krichel, C. Uetrecht, M. Fischer, and M. Wilmanns, The crystal structure of mycobacterial epoxide hydrolase A, Scientific Reports 10 (1), 16539 (2020).

P. Mehrabi, H. Müller-Werkmeister, J.-P. Leimkohl, H. Schikora, J. Ninkovic, S. Krivokuca, L. Andriček, S. W. Epp, D. Sherrell, R. L. Owen, A. R. Pearson, F. Tellkamp, E.-C. Schulz, and R. J. D. Miller, The HARE chip for efficient time-resolved serial synchrotron crystallography, Journal of Synchrotron Radiation; Wiley-Blackwell on behalf of the IUCr 27 (2), 360–370 (2020).

R. Bücker, P. Hogan-Lamarre, P. Mehrabi, E.-C. Schulz, L. Bultema, Y. Gevorkov, W. Brehm, O. Yefanov, D. Oberthür, G. Kassier, and R. J. D. Miller, Serial protein crystallography in an electron microscope, Nature Communications 11 (1), 996 (2020).

P. Mehrabi, E.-C. Schulz, M. Agthe, S. Horrell, G. Bourenkov, D. von Stetten, J.-P. Leimkohl, H. Schikora, T. R. Schneider, A. R. Pearson, F. Tellkamp, and R. J. D. Miller, Liquid application method for time-resolved analyses by serial synchrotron crystallography, Nature methods 16 (10), 979–982 (2019).

P. Mehrabi, E.-C. Schulz, R. Dsouza, H. Müller-Werkmeister, F. Tellkamp, R. J. D. Miller, and E. F. Pai, Time-resolved crystallography reveals allosteric communication aligned with molecular breathing, Science 365 (6458), 1167–1170 (2019).

E.-C. Schulz, P. Mehrabi, H. Müller-Werkmeister, F. Tellkamp, A. Jha, W. Stuart, E. Persch, R. De Gasparo, F. Diederich, E. F. Pai, and R. J. D. Miller, The hit-and-return system enables efficient time-resolved serial synchrotron crystallography, Nature methods 15 (11), 901–904 (2018).

E.-C. Schulz, J. Kaub, F. Busse, P. Mehrabi, H. Müller-Werkmeister, E. F. Pai, W. Robertson, and R. J. D. Miller, Protein crystals IR laser ablated from aqueous solution at high speed retain their diffractive properties: applications in high-speed serial crystallography, Journal of Applied Crystallography 50, 1773–1781 (2017).

R. L. Owen, D. Axford, D. A. Sherrell, A. Kuo, O. P. Ernst, E.-C. Schulz, R. J. D. Miller, and H. Müller-Werkmeister, Low-dose fixed-target serial synchrotron crystallography, Acta Crystallographica Section D: Structural Biology 73, 373–378 (2017).

P. Mehrabi and E.-C. Schulz, Sample Preparation for Time-Resolved Serial Crystallography: Practical Considerations, in Advanced Methods in Structural Biology, A. Sousa and L. Passarinha, Eds. Berlin/Heidelberg: Springer Science+Business Media, 2023, , 361–379 .

P. Mehrabi, E.-C. Schulz, H. M. Müller-Werkmeister, E. Persch, R. D. Gasparo, F. Diederich, F. Tellkamp, E. Pai, and R. J. D. Miller, Time-resolved crystallography via an interlacing approach allows elucidation of milliseconds to seconds time delays, in Acta Crystallographica Section A: Foundations and Advances, Oviedo, Spain, 2018, 74, , e138–e138MS38-O4 .

H. Müller-Werkmeister, E.-C. Schulz, D. Sherrell, D. Axford, F. Tellkamp, R. L. Owen, and R. J. D. Miller, Serial Synchrotron Cryallography with a Fixed Target, in Biophysical Journal, San Francisco, CA, 2017, 3rd ed. 112, , 579A–579A .

P. Mehrabi, D. von Stetten, J.-P. Leimkohl, F. Tellkamp, and E.-C. Schulz, An environmental control box for serial crystallography enables multi-dimensional experiments. 08-Nov-2021.

S. Günther, P. Y. A. Reinke, D. Oberthuer, O. Yefanov, H. Ginn, S. Meier, T. J. Lane, K. Lorenzen, L. Gelisio, W. Brehm, I. Dunkel, M. Domaracky, S. Saouane, J. Lieske, C. Ehrt, F. Koua, A. Tolstikova, T. A. White, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, L. X. Paulraj, M. Barthelmess, F. Schlünzen, N. Werner, H. Andaleeb, N. Ullah, S. Falke, B. A. Franca, M. Schwinzer, H. Brognaro, B. Seychell, H. Gieseler, D. Melo, J. J. Zaitsev-Doyle, B. Norton-Baker, J. Knoska, G. Esperanza, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, C. Rogers, D. C. F. Monteiro, J. Hakanpää, J. Meyer, H. Noei, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. Feiler, M. Weiss, E.-C. Schulz, P. Mehrabi, C. Schmidt, R. Schubert, H. Han, B. Krichel, Y. Fernández-García, B. Escudero-Pérez, S. Günther, D. Turk, C. Uetrecht, T. Beck, H. Tidow, A. Chari, A. Zaliani, M. Rarey, R. Cox, R. Hilgenfeld, H. N. Chapman, A. R. Pearson, C. Betzel, and A. Meents, Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease. 04-May-2020.