Fixed-target serial oscillation crystallography at room temperature
J. L. Wierman, O. Paré-Labrosse, A. Sarracini, J. E. Besaw, M. J. Cook, S. Oghbaey, H. Daoud, P. Mehrabi, I. Kriksunov, A. Kuo, D. J. Schuller, S. Smith, O. P. Ernst, D. M. E. Szebenyi, S. M. Gruner, R. J. D. Miller, A. D. Finkea
X-ray screening has revealed several promising candidates for drugs against the coronavirus. The collaborative DESY-led study, which involved the MPSD and many other organisations, discovered seven substances which inhibit the activity of the main protease and thus slow down the multiplication of the virus. Two of them are particularly promising candidates.
Although they operate on very different timescales, synchrotrons and XFELs can produce data of equivalent quality as long as serial data collection is used in the imaging process, according to a new study. The findings open up a new avenue for collaborative applications.
Scientists pioneer an approach called self-referenced streaking, clocking Auger electrons with sub-femtosecond resolution. The breakthrough will unlock the broader potential for attosecond time resolution at X-ray free-electron lasers.
Electron spin is one of the most fundamental quantities defining the properties of molecules. A new study by a research team from Germany, Canada, Poland, and Lebanon offers a detailed understanding on how changes in spin states affect the nuclear configuration as a probe of the change in electron distribution by directly observing the atomic motions and changes in the molecular structure, driven by change in electron spin.
Researchers from the Department of Atomically Resolved Dynamics of the MPSD (Max Planck Institute for the Structure and Dynamics of Matter) at the Center for Free-Electron Laser Science in Hamburg, the University of Toronto in Canada and the ETH in Zurich, Switzerland, have developed a new method to watch biomolecules at work.