Publications of P. Mehrabi

C. E. Hatton and P. Mehrabi, Exploring the dynamics of allostery through multi-dimensional crystallography, Biophysical Reviews 16 (5), 563–570 (2024).

J. M. Baxter, C. D. M. Hutchison, A. Fadini, K. Maghlaoui, V. Cordon-Preciado, R. M. L. Morgan, M. Agthe, S. Horrell, F. Tellkamp, P. Mehrabi, Y. Pfeifer, H. M. Müller-Werkmeister, D. von Stetten, A. R. Pearson, and J. J. van Thor, Power Density Titration of Reversible Photoisomerization of a Fluorescent Protein Chromophore in the Presence of Thermally Driven Barrier Crossing Shown by Quantitative Millisecond Serial Synchrotron X-ray Crystallography, Journal of the American Chemical Society 146 (24), 16394–16403 (2024).

R. Bosman, A. Prester, S. Sung, L. von Soosten, S. Dibenedetto, K. Bartels, D. von Stetten, P. Mehrabi, M. Blatter, G. Lu, B. Suer, M. Wilmanns, M. Osbild, and E.-C. Schulz, A systematic comparison of Kapton-based HARE chips for fixed-target serial crystallography, Cell Reports Physical Science 5 (6), 101987 (2024).

A. Berkes, S. Kleine-Doepke, J.-P. Leimkohl, H. Schikora, P. Mehrabi, F. Tellkamp, and E.-C. Schulz, An electropneumatic cleaning device for piezo-actuator-driven picolitre-droplet dispensers, Journal of Applied Crystallography 57 (1), 209–214 (2024).

P. Mehrabi, S. Sung, D. von Stetten, A. Prester, C. E. Hatton, S. Kleine-Döpke, A. Berkes, G. Gore, J.-P. Leimkohl, H. Schikora, M. Kollewe, H. Rohde, M. Wilmanns, F. Tellkamp, and E.-C. Schulz, Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography, Nature Communications 14 (1), 2365 (2023).

B. Norton-Baker, P. Mehrabi, A. O. Kwok, K. W. Roskamp, M. A. Rocha, M. A. Sprague-Piercy, D. von Stetten, R. J. D. Miller, and R. W. Martin, Deamidation of the human eye lens protein γS-crystallin accelerates oxidative aging, Structure 30 (5), 763–776 (2022).

B. Norton-Baker, P. Mehrabi, J. Boger, R. Schönherr, D. von Stetten, H. Schikora, A. O. Kwok, R. W. Martin, R. J. D. Miller, L. Redecke, and E.-C. Schulz, A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip, Acta Crystallographica Section D: Structural Biology 77 (6), D77 (2021).

S. Günther, P. Y. A. Reinke, Y. Fernández-García, J. Lieske, T. J. Lane, H. M. Ginn, F. H. M. Koua, C. Ehrt, W. Ewert, D. Oberthuer, O. Yefanov, S. Meier, K. Lorenzen, B. Krichel, J.-D. Kopicki, L. Gelisio, W. Brehm, I. Dunkel, B. Seychell, H. Gieseler, B. Norton-Baker, B. Escudero-Pérez, M. Domaracky, S. Saouane, A. Tolstikova, T. A. White, A. Hänle, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, M. Barthelmess, F. Schlünzen, L. X. Paulraj, N. Werner, H. Andaleeb, N. Ullah, S. Falke, V. Srinivasan, B. A. Franca, M. Schwinzer, H. Brognaro, C. Rogers, D. Melo, J. J. Zaitsev-Doyle, J. Knoska, G. E. P. Murillo, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, J. Hakanpää, J. Meyer, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, A. R. Beccari, G. Bourenkov, D. von Stetten, G. Pompidor, I. Bento, S. Panneerselvam, I. Karpics, T. R. Schneider, M. M. G. Alai, S. Niebling, C. Günther, C. Schmidt, R. Schubert, H. Han, J. Boger, D. C. F. Monteiro, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. G. Feiler, M. S. Weiss, E.-C. Schulz, P. Mehrabi, K. Karničar, A. Usenik, J. Loboda, H. Tidow, A. Chari, R. Hilgenfeld, C. Uetrecht, R. Cox, A. Zaliani, T. Beck, M. Rarey, S. Günther, D. Turk, W. Hinrichs, H. N. Chapman, A. .R. Pearson, C. Betzel, and A. Meents, X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease, Science 372 (6542), 642–646 (2021).

P. Mehrabi, R. Bücker, G. Bourenkov, H. Ginn, D. von Stetten, H. M. Mueller-Werkmeister, A. Kuo, T. Morizumi, B. Eger, W.-L. Ou, S. Oghbaey, A. Sarracini, J. Besaw, O. Paré-Labrosse, S. Meier, H. Schikora, F. Tellkamp, A. Marx, D. A. Sherrell, D. Axford, R. L. Owen, O. P. Ernst, E. F. Pai, E.-C. Schulz, and R. J. D. Miller, Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison, Science Advances 7 (12), eabf1380 (2021).

A. R. Pearson and P. Mehrabi, Serial synchrotron crystallography for time-resolved structural biology, Current Opinion in Structural Biology 65, 168–174 (2020).

P. Mehrabi, H. Müller-Werkmeister, J.-P. Leimkohl, H. Schikora, J. Ninkovic, S. Krivokuca, L. Andriček, S. W. Epp, D. Sherrell, R. L. Owen, A. R. Pearson, F. Tellkamp, E.-C. Schulz, and R. J. D. Miller, The HARE chip for efficient time-resolved serial synchrotron crystallography, Journal of Synchrotron Radiation; Wiley-Blackwell on behalf of the IUCr 27 (2), 360–370 (2020).

R. Bücker, P. Hogan-Lamarre, P. Mehrabi, E.-C. Schulz, L. Bultema, Y. Gevorkov, W. Brehm, O. Yefanov, D. Oberthür, G. Kassier, and R. J. D. Miller, Serial protein crystallography in an electron microscope, Nature Communications 11 (1), 996 (2020).

P. Mehrabi, E.-C. Schulz, M. Agthe, S. Horrell, G. Bourenkov, D. von Stetten, J.-P. Leimkohl, H. Schikora, T. R. Schneider, A. R. Pearson, F. Tellkamp, and R. J. D. Miller, Liquid application method for time-resolved analyses by serial synchrotron crystallography, Nature methods 16 (10), 979–982 (2019).

P. Mehrabi, E.-C. Schulz, R. Dsouza, H. Müller-Werkmeister, F. Tellkamp, R. J. D. Miller, and E. F. Pai, Time-resolved crystallography reveals allosteric communication aligned with molecular breathing, Science 365 (6458), 1167–1170 (2019).

P. Mehrabi, C. D. Pietrantonio, T. H. Kim, A. Sljoka, K. Taverner, C. Ing, N. Kruglyak, R. Pomès, E. F. Pai, and R. S. Prosser, Substrate-Based Allosteric Regulation of a Homodimeric Enzyme, Journal of the American Chemical Society 141 (29), 11540–11556 (2019).

J. L. Wierman, O. Paré-Labrosse, A. Sarracini, J. E. Besaw, M. J. Cook, S. Oghbaey, H. Daoud, P. Mehrabi, I. Kriksunov, A. Kuo, D. J. Schuller, S. Smith, O. P. Ernst, D. M. E. Szebenyi, S. M. Gruner, R. J. D. Miller, and A. D. Finkea, Fixed-target serial oscillation crystallography at room temperature, IUCrJ 6, 305–316 (2019).

E.-C. Schulz, P. Mehrabi, H. Müller-Werkmeister, F. Tellkamp, A. Jha, W. Stuart, E. Persch, R. De Gasparo, F. Diederich, E. F. Pai, and R. J. D. Miller, The hit-and-return system enables efficient time-resolved serial synchrotron crystallography, Nature methods 15 (11), 901–904 (2018).

P. Mehrabi and E.-C. Schulz, Sample Preparation for Time-Resolved Serial Crystallography: Practical Considerations, in Advanced Methods in Structural Biology, A. Sousa and L. Passarinha, Eds. Berlin/Heidelberg: Springer Science+Business Media, 2023, , 361–379 .

P. Mehrabi, E.-C. Schulz, H. M. Müller-Werkmeister, E. Persch, R. D. Gasparo, F. Diederich, F. Tellkamp, E. Pai, and R. J. D. Miller, Time-resolved crystallography via an interlacing approach allows elucidation of milliseconds to seconds time delays, in Acta Crystallographica Section A: Foundations and Advances, Oviedo, Spain, 2018, 74, , e138–e138MS38-O4 .

E.-C. Schulz, A. Prester, D. von Stetten, G. Gore, C. E. Hatton, K. Bartels, J.-P. Leimkohl, H. Schikora, H. M. Ginn, F. Tellkamp, and P. Mehrabi, Probing the modulation of enzyme kinetics by multi-temperature, time-resolved serial crystallography. 24-Jul-2024.