Publications of P. Mehrabi

Journal Article (14)

2024
Journal Article
An electropneumatic cleaning device for piezo-actuator-driven picolitre-droplet dispensers
Journal of Applied Crystallography 57 (1), 209–214 (2024)
2023
Journal Article
Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography
P. Mehrabi, S. Sung, D. von Stetten, A. Prester, C. E. Hatton, S. Kleine-Döpke, A. Berkes, G. Gore, J.-P. Leimkohl, H. Schikora, M. Kollewe, H. Rohde, M. Wilmanns, F. Tellkamp, E.-C. Schulz
Nature Communications 14 (1), 2365 (2023)
2022
Journal Article
Deamidation of the human eye lens protein γS-crystallin accelerates oxidative aging
B. Norton-Baker, P. Mehrabi, A. O. Kwok, K. W. Roskamp, M. A. Rocha, M. A. Sprague-Piercy, D. von Stetten, R. J. D. Miller, R. W. Martin
Structure 30 (5), 763–776 (2022)
2021
Journal Article
A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip
B. Norton-Baker, P. Mehrabi, J. Boger, R. Schönherr, D. von Stetten, H. Schikora, A. O. Kwok, R. W. Martin, R. J. D. Miller, L. Redecke, E.-C. Schulz
Acta Crystallographica Section D: Structural Biology 77 (6), D77 (2021)
Journal Article
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
S. Günther, P. Y. A. Reinke, Y. Fernández-García, J. Lieske, T. J. Lane, H. M. Ginn, F. H. M. Koua, C. Ehrt, W. Ewert, D. Oberthuer, O. Yefanov, S. Meier, K. Lorenzen, B. Krichel, J.-D. Kopicki, L. Gelisio, W. Brehm, I. Dunkel, B. Seychell, H. Gieseler, B. Norton-Baker, B. Escudero-Pérez, M. Domaracky, S. Saouane, A. Tolstikova, T. A. White, A. Hänle, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, M. Barthelmess, F. Schlünzen, L. X. Paulraj, N. Werner, H. Andaleeb, N. Ullah, S. Falke, V. Srinivasan, B. A. Franca, M. Schwinzer, H. Brognaro, C. Rogers, D. Melo, J. J. Zaitsev-Doyle, J. Knoska, G. E. P. Murillo, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, J. Hakanpää, J. Meyer, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, A. R. Beccari, G. Bourenkov, D. von Stetten, G. Pompidor, I. Bento, S. Panneerselvam, I. Karpics, T. R. Schneider, M. M. G. Alai, S. Niebling, C. Günther, C. Schmidt, R. Schubert, H. Han, J. Boger, D. C. F. Monteiro, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. G. Feiler, M. S. Weiss, E.-C. Schulz, P. Mehrabi, K. Karničar, A. Usenik, J. Loboda, H. Tidow, A. Chari, R. Hilgenfeld, C. Uetrecht, R. Cox, A. Zaliani, T. Beck, M. Rarey, S. Günther, D. Turk, W. Hinrichs, H. N. Chapman, A. .R. Pearson, C. Betzel, A. Meents
Science 372 (6542), 642–646 (2021)
Journal Article
Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison
P. Mehrabi, R. Bücker, G. Bourenkov, H. Ginn, D. von Stetten, H. M. Mueller-Werkmeister, A. Kuo, T. Morizumi, B. Eger, W.-L. Ou, S. Oghbaey, A. Sarracini, J. Besaw, O. Paré-Labrosse, S. Meier, H. Schikora, F. Tellkamp, A. Marx, D. A. Sherrell, D. Axford, R. L. Owen, O. P. Ernst, E. F. Pai, E.-C. Schulz, R. J. D. Miller
Science Advances 7 (12), eabf1380 (2021)
2020
Journal Article
Serial synchrotron crystallography for time-resolved structural biology
A. R. Pearson, P. Mehrabi
Current Opinion in Structural Biology 65, 168–174 (2020)
Journal Article
The HARE chip for efficient time-resolved serial synchrotron crystallography
P. Mehrabi, H. Müller-Werkmeister, J.-P. Leimkohl, H. Schikora, J. Ninkovic, S. Krivokuca, L. Andriček, S. W. Epp, D. Sherrell, R. L. Owen, A. R. Pearson, F. Tellkamp, E.-C. Schulz, R. J. D. Miller
Journal of Synchrotron Radiation; Wiley-Blackwell on Behalf of the IUCr 27 (2), 360–370 (2020)
Journal Article
Serial protein crystallography in an electron microscope
R. Bücker, P. Hogan-Lamarre, P. Mehrabi, E.-C. Schulz, L. Bultema, Y. Gevorkov, W. Brehm, O. Yefanov, D. Oberthür, G. Kassier, R. J. D. Miller
Nature Communications 11 (1), 996 (2020)
2019
Journal Article
Liquid application method for time-resolved analyses by serial synchrotron crystallography
P. Mehrabi, E.-C. Schulz, M. Agthe, S. Horrell, G. Bourenkov, D. von Stetten, J.-P. Leimkohl, H. Schikora, T. R. Schneider, A. R. Pearson, F. Tellkamp, R. J. D. Miller
Nature Methods 16 (10), 979–982 (2019)
Journal Article
Time-resolved crystallography reveals allosteric communication aligned with molecular breathing
Science 365 (6458), 1167–1170 (2019)
Journal Article
Substrate-Based Allosteric Regulation of a Homodimeric Enzyme
P. Mehrabi, C. D. Pietrantonio, T. H. Kim, A. Sljoka, K. Taverner, C. Ing, N. Kruglyak, R. Pomès, E. F. Pai, R. S. Prosser
Journal of the American Chemical Society 141 (29), 11540–11556 (2019)
Journal Article
Fixed-target serial oscillation crystallography at room temperature
J. L. Wierman, O. Paré-Labrosse, A. Sarracini, J. E. Besaw, M. J. Cook, S. Oghbaey, H. Daoud, P. Mehrabi, I. Kriksunov, A. Kuo, D. J. Schuller, S. Smith, O. P. Ernst, D. M. E. Szebenyi, S. M. Gruner, R. J. D. Miller, A. D. Finkea
IUCrJ 6, 305–316 (2019)
2018
Journal Article
The hit-and-return system enables efficient time-resolved serial synchrotron crystallography
E.-C. Schulz, P. Mehrabi, H. Müller-Werkmeister, F. Tellkamp, A. Jha, W. Stuart, E. Persch, R. De Gasparo, F. Diederich, E. F. Pai, R. J. D. Miller
Nature Methods 15 (11), 901–904 (2018)

Book Chapter (1)

2023
Book Chapter
Sample Preparation for Time-Resolved Serial Crystallography: Practical Considerations
In: A. Sousa, L. Passarinha, editors. Advanced Methods in Structural Biology, Berlin/Heidelberg: Springer Science+Business Media; 2023, p. 361–379

Conference Paper (1)

2018
Conference Paper
Time-resolved crystallography via an interlacing approach allows elucidation of milliseconds to seconds time delays
P. Mehrabi, E.-C. Schulz, H. M. Müller-Werkmeister, E. Persch, R. D. Gasparo, F. Diederich, F. Tellkamp, E. Pai, R. J. D. Miller
Acta Crystallographica Section A: Foundations and Advances, vol. 74, IUCr/Wiley; 2018, p. e138–e138

Preprint (2)

2021
Preprint
An environmental control box for serial crystallography enables multi-dimensional experiments
(2021)
2020
Preprint
Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease
S. Günther, P. Y. A. Reinke, D. Oberthuer, O. Yefanov, H. Ginn, S. Meier, T. J. Lane, K. Lorenzen, L. Gelisio, W. Brehm, I. Dunkel, M. Domaracky, S. Saouane, J. Lieske, C. Ehrt, F. Koua, A. Tolstikova, T. A. White, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, L. X. Paulraj, M. Barthelmess, F. Schlünzen, N. Werner, H. Andaleeb, N. Ullah, S. Falke, B. A. Franca, M. Schwinzer, H. Brognaro, B. Seychell, H. Gieseler, D. Melo, J. J. Zaitsev-Doyle, B. Norton-Baker, J. Knoska, G. Esperanza, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, C. Rogers, D. C. F. Monteiro, J. Hakanpää, J. Meyer, H. Noei, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. Feiler, M. Weiss, E.-C. Schulz, P. Mehrabi, C. Schmidt, R. Schubert, H. Han, B. Krichel, Y. Fernández-García, B. Escudero-Pérez, S. Günther, D. Turk, C. Uetrecht, T. Beck, H. Tidow, A. Chari, A. Zaliani, M. Rarey, R. Cox, R. Hilgenfeld, H. N. Chapman, A. R. Pearson, C. Betzel, A. Meents
(2020)
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